Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required)

National Institutes of Health · United States government procurement

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October 11, 2026
Response Due
Active
Status

Opportunity Overview

The purpose of this notice of funding opportunity (NOFO) is to elucidate the key components of the therapeutic effects of rapid-acting psychotropic interventional drugs (RAPIDs) by addressing the methodological challenges involved with these clinical trials. In addition, this NOFO seeks to advance understanding of how RAPIDs and adjunctive psychosocial interventions can be optimally delivered, monitored, and sustained over time to enhance effectiveness and generalizability. The NOFO will support studies designed to enhance the rigor of RAPID clinical trial design, which will ultimately increase the interpretability of the data and the generalizability of the results.

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Solicitation Details

Issuing agencyNational Institutes of Health
CountryUnited States
CategoryMental Health
NAICS93.242, 93.279
PublishedApril 29, 2026
Procurement stageRequest for Proposal (RFP)
Response dueOctober 11, 2026
StatusOpen — accepting responses
Official sourceView original notice
Last verifiedAugust 10, 2026

Source: U.S. Government (Grants.gov) — public domain. Not affiliated with or endorsed by the United States Government.

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