The Genesis Mission: Transforming Science and Energy with AI

Office of Science · United States government procurement

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December 17, 2026
Response Due
Active
Status

Opportunity Overview

<p><span style="color: black;">The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the </span><a href="https://www.energy.gov/documents/genesis-mission-science-and-technology-challenges?utm_medium=email&amp;utm_source=govdelivery" target="_blank">Genesis Mission National Science and Technology Challenges</a><span style="color: black;"> to accelerate scientific discovery and research and development (R&amp;D) workflows using novel artificial intelligence (AI) models and frameworks.&nbsp;By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology.&nbsp;Teams are encouraged to leverage the extensive scientific and data resources of the DOE/National Nuclear Security Administration (NNSA), the National Laboratories, U.S. industry, and academia.&nbsp;The resulting AI models and workflows, if successful, may be integrated into the American Science Cloud.</span></p> <p><span style="color: black;">&nbsp;</span></p> <p><span style="color: black;">DOE is soliciting new FY26 Phase I small team and Phase II large team applications in the following topic areas:&nbsp;advanced manufacturing, biotechnology, critical materials, nuclear fission, nuclear fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy (see specific focus areas in </span>Section III<span style="color: black;"> Program Descriptions).</span></p> <p><span style="color: black;">&nbsp;</span></p> <p><span style="color: black;">In addition, this RFA will remain available to allow the recipients of FY26 Phase I awards to apply for larger team Phase II...

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Solicitation Details

Issuing agencyOffice of Science
CountryUnited States
CategoryEnergy
NAICS81.049
PublishedMarch 17, 2026
Procurement stageRequest for Proposal (RFP)
Response dueDecember 17, 2026
StatusOpen — accepting responses
Official sourceView original notice
Last verifiedAugust 12, 2026

Source: U.S. Government (Grants.gov) — public domain. Not affiliated with or endorsed by the United States Government.

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