Office-Wide Innovative Solutions Opening for Health Science Futures (HSF)

This ISO seeks solution summaries and proposal submissions for projects that fall within the general scope of the ARPA-H Health Science Futures (HSF) mission office. HSF expands what is technically possible by developing approaches that will remove the scientific and technological limitations that stymie progress towards the healthcare of the future. HSF supports cutting-edge, often disease-agnostic research programs that have the potential for translational real-world change. Solution summary submissions must be submitted to: https://solutions.arpa-h.gov Questions must be submitted to: https://solutions.arpa-h.gov/Ask-A-Question/ Proposal submission should be submitted to: https://solutions.arpa-h.gov/Submit-Proposal/ Amendment 1 is effective immediately; however, if an entity has previously submitted a solution summary and/or a proposal, the base solicitation will be followed for those submissions. If a solution summary is submitted; however, a proposal has not been submitted yet, the proposal will be evaluated in accordance with this amendment. The amendment: Removes the option to submit a proposal through Grants.gov in Section 1 and Section 4.4. Removes the option for a proposer to submit a solution summary and proposal at the same time. Language is deleted in Section 2.2 and Section 5.1. Removes duplicative language about the type of eligible proposers in Section 3.1 because language is found in Section 2.2. Incorporates language in Section 3.2 to show �FFRDCs and government entities, including federal government employees, are not permitted to respond to this solicitation�� and includes information on how handle unique proposal situations. Incorporates language in Section 3.5 to encourage submission of research ideas notwithstanding any potential ARPA-H award limitations. Incorporates language in Section 4.1 to expand on the reasoning for requiring solution summaries. Incorporates language in Section 4.4 to clarify required documents for other transaction and...