Proactive Health Office (PHO) Mission Office Innovative Solutions Opening (ISO)

Health and Human Services, Department of · United States government procurement

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March 05, 2029
Response Due
Active
Status

Opportunity Overview

The Proactive Health Office (PHO) at ARPA-H is seeking solutions to improve the healthspan and health outcomes of Americans prior to the onset of disease and/or the development of diminished quality of life from illness. Specifically, PHO hypothesizes that 1) population-level improvements in access to and uptake of disease prevention and wellness-promoting behaviors and 2) development of novel early-detection methods and prophylactic interventions could drastically improve the health of American throughout their lives, and 3) that system level innovations are required for delivery of proactive health effectively. Solution summary submissions must be submitted to: https://solutions.arpa-h.gov Questions must be submitted to: https://solutions.arpa-h.gov/Ask-A-Question/ Proposal submission should be submitted to: https://solutions.arpa-h.gov/Submit-Proposal/ Amendment 3 is effective immediately; however, if an entity has previously submitted a solution summary and/or a proposal, the prior solicitation(s) will be followed for those submissions. If a solution summary is submitted; however, a proposal has not been submitted yet, the proposal will be evaluated in accordance with this amendment. The following updates were made to the proposal documents: 1) Administrative & National Policy Requirements Document Updated the instructions and references within the �Organizational Conflicts of Interest (OCI) Affirmations and Disclosure� section. Updated questions, instructions, and content within the �Research Security Disclosure� section. Updated the instructions and intellectual property data assertions charts within the �IP� section. This included providing definitions of rights categories (unlimited, government purpose, limited, and specially negotiated/other) and consolidating two data assertions charts into one to assist proposers more efficiently complete the document. Specifically, the �Non-Commercial� and �Commercial� tables were removed and replaced with the...

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Solicitation Details

Issuing agencyHealth and Human Services, Department of
CountryUnited States
CategoryGovernment Procurement
NAICS541715
PSCAN13
PublishedNovember 13, 2025
Procurement stageRequest for Proposal (RFP)
Response dueMarch 05, 2029
StatusOpen — accepting responses
Official sourceView original notice
Last verifiedOctober 11, 2026

Source: U.S. Government (SAM.gov) — public domain. GlobalGov is not affiliated with or endorsed by the United States Government.

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